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Can we individualize the ‘number needed to treat’?...
Journal article

Can we individualize the ‘number needed to treat’? An empirical study of summary effect measures in meta-analyses

Abstract

BACKGROUND: Meta-analyses summarize the magnitude of treatment effect using a number of measures of association, including the odds ratio (OR), risk ratio (RR), risk difference (RD) and/or number needed to treat (NNT). In applying the results of a meta-analysis to individual patients, some textbooks of evidence-based medicine advocate individualizing NNT, based on the RR and the patient's expected event rate (PEER). This approach assumes …

Authors

Furukawa TA; Guyatt GH; Griffith LE

Journal

International Journal of Epidemiology, Vol. 31, No. 1, pp. 72–76

Publisher

Oxford University Press (OUP)

Publication Date

February 1, 2002

DOI

10.1093/ije/31.1.72

ISSN

0300-5771