Journal article
A Comprehensive Analysis of Mammalian Mitochondrial Genome Base Composition and Improved Phylogenetic Methods
Abstract
Phylogenetic analysis of mammalian species using mitochondrial protein genes has proved to be problematic in many previous studies. The high mutation rate of mitochondrial DNA and unusual base composition of several species has prompted us to conduct a detailed study of the composition of 69 mammalian mitochondrial genomes. Most major changes in base composition between lineages can be attributed to shifts between the proportions of C and T on …
Authors
Gibson A; Gowri-Shankar V; Higgs PG; Rattray M
Journal
Molecular Biology and Evolution, Vol. 22, No. 2, pp. 251–264
Publisher
Oxford University Press (OUP)
Publication Date
February 1, 2005
DOI
10.1093/molbev/msi012
ISSN
0737-4038