Studies relating to the accuracy of in vivo measurements of liver and kidney cadmium

A greater understanding of the inaccuracies involved inin vivo measurements of liver and kidney cadmium by neutron activation was necessary. Studies were therefore carried out, using phantoms, into the effect onin vivo measurement accuracy of organ depth and organ mass. In addition an independentin vitro technique was developed, and used to analyse autopsy samples from three people previously measuredin vivo, thus making direct comparisons possible. No evidence of bias in thein vivo results was found, but the need to correct for organ mass and depth was highlighted. Current measurement procedures result in residual uncertainties of ±25%.