Influence of oral and subcutaneous bisphenol-A on intrauterine implantation of fertilized ova in inseminated female mice

Intrauterine implantation of fertilized ova in inseminated females is sensitive to minute levels of natural estrogens. Bisphenol-A (BPA), a widely used chemical in the production of polycarbonate plastics and epoxy resins, can be estrogenic. Here we administered BPA during the period of implantation to determine levels of exposure required to terminate pregnancy in mice. Varied doses were given through either injection or ingestion. …