Journal article
Triclosan elevates estradiol levels in serum and tissues of cycling and peri-implantation female mice
Abstract
Triclosan, an antimicrobial agent added to personal care products, can modulate estrogenic actions. We investigated whether triclosan affects concentrations of exogenous and endogenous estradiol. Female mice were given injections of triclosan followed by 1μCi tritium-labeled estradiol. Mice given daily 2-mg triclosan doses (57.9mg/kg/dose) showed significantly elevated radioactivity in tissues and serum compared to controls. A single dose of 1 …
Authors
Pollock T; Greville LJ; Tang B; deCatanzaro D
Journal
Reproductive Toxicology, Vol. 65, , pp. 394–401
Publisher
Elsevier
Publication Date
October 2016
DOI
10.1016/j.reprotox.2016.09.004
ISSN
0890-6238