Journal article
Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dysfunction in patients with heart failure. SOLVD Investigators.
Abstract
BACKGROUND: In patients with heart failure, activation of the renin-angiotensin system is common and has been postulated to provide a stimulus for further left ventricular (LV) structural and functional derangement. We tested the hypothesis that chronic administration of the angiotensin converting enzyme (ACE) inhibitor enalapril prevents or reverses LV dilatation and systolic dysfunction among patients with depressed ejection fraction (EF) and …
Authors
Konstam MA; Rousseau MF; Kronenberg MW; Udelson JE; Melin J; Stewart D; Dolan N; Edens TR; Ahn S; Kinan D
Journal
Circulation, Vol. 86, No. 2, pp. 431–438
Publisher
Wolters Kluwer
Publication Date
August 1992
DOI
10.1161/01.cir.86.2.431
ISSN
0009-7322