Journal article
The effect of DNA probe distribution on the reliability of label-free biosensors
Abstract
As the design of label-free DNA biosensors matures, and their sizes reduced to enhance their sensitivity, not much has been researched about the variations in the received signal with the positioning of the probes on the sensitive surface. We approach this issue computationally in this paper. By adopting the finite-element model on a three-dimensional biological field-effect transistor (BioFET) slice, and running Monte-Carlo simulations on the …
Authors
Shinwari MW; Shinwari MF; Deen MJ; Selvaganapathy PR
Journal
Sensors and Actuators B Chemical, Vol. 160, No. 1, pp. 441–447
Publisher
Elsevier
Publication Date
December 2011
DOI
10.1016/j.snb.2011.08.006
ISSN
0925-4005