Functionalized Carborane Complexes of the [M(CO)2(NO)]2+ Core (M = 99mTc, Re): A New Class of Organometallic Probes for Correlated in Vitro and in Vivo Imaging

Functionalized carborane complexes of the [M(CO)2(NO)]2+ (M = Re, 99mTc) core have potential utility as matched pairs of probes for correlated optical (M = Re) and scintigraphic (M = 99mTc) imaging. A synthetic route to closo-rhenacarboranes of the type [Re(CO)2(NO)(RR′C2B9H9)] in a manner suitable for the preparation of the radioactive technetium-99m analogues has been developed, resulting in the isolation of four novel metallacarboranes …