Journal article
Delayed expression of enhanced reactivation and decreased mutagenesis of UV-irradiated adenovirus in UV-irradiated ataxia telangiectasia fibroblasts
Abstract
Fibroblasts from patients with ataxia telangiectasia (AT) are hypersensitive to the lethal effects but hyposensitive to the mutagenic effects of ionizing radiation, suggesting that AT cells may be defective in some process which modifies damage to DNA. In this study we have examined the UV-enhanced reactivation (UVER) and UV-enhanced mutagenesis (UVEM) of UV-irradiated adenovirus in AT fibroblasts. UVER was examined using both V antigen …
Authors
Bennett CB; Rainbow AJ
Journal
Mutagenesis, Vol. 3, No. 5, pp. 389–395
Publisher
Oxford University Press (OUP)
Publication Date
1988
DOI
10.1093/mutage/3.5.389
ISSN
0267-8357