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Assessment of DNA Oxidation and Antioxidant...
Journal article

Assessment of DNA Oxidation and Antioxidant Activity in Hypertensive Patients with Chronic Kidney Disease

Abstract

The aim of this study was to evaluate the oxidative DNA damage, antioxidant activity, and effects of antihypertensive drugs on oxidative stress in hypertensive patients with different stages of chronic kidney disease (CKD). Fifty-three non-dialyzed hypertensive CKD patients were included by the study. Serum and urinary 8-hydroxydeoxy guanosine (8-OHdG) levels (as a marker of oxidative DNA damage), serum superoxide dismutase (SOD), and …

Authors

Dincer Y; Sekercioglu N; Pekpak M; Gunes KN; Akcay T

Journal

Renal Failure, Vol. 30, No. 10, pp. 1006–1011

Publisher

Taylor & Francis

Publication Date

1 2008

DOI

10.1080/08860220802422044

ISSN

0886-022X