Journal article
Direct Profiling of Cancer Biomarkers in Tumor Tissue Using a Multiplexed Nanostructured Microelectrode Integrated Circuit
Abstract
The analysis of panels of nucleic acid biomarkers offers valuable diagnostic and prognostic information for cancer management. A cost-effective, highly sensitive electronic chip would offer an ideal platform for clinical biomarker readout and would have maximal utility if it was (i) multiplexed, enabling on-chip assays of multiple biomarkers, and (ii) able to perform direct (PCR-free) readout of disease-related genes. Here we report a chip onto …
Authors
Fang Z; Soleymani L; Pampalakis G; Yoshimoto M; Squire JA; Sargent EH; Kelley SO
Journal
ACS Nano, Vol. 3, No. 10, pp. 3207–3213
Publisher
American Chemical Society (ACS)
Publication Date
October 27, 2009
DOI
10.1021/nn900733d
ISSN
1936-0851