Journal article
Systemic bone formation with weekly PTH administration in ovariectomized rats.
Abstract
PURPOSE: Weekly subcutaneous administration of 0 (vehicle), 10 and 80 microg/kg doses of human parathyroid hormone (1-34) [PTH (1-34)] were compared based on their capacity to induce systemic formation of bone in 9 month-old ovariectomized (OVX) Sprague-Dawley rats.
METHODS: Changes elicited at bone tissue after 4 weeks of treatment were assessed using dual x-ray absorptiometry, micro-computed tomography (microCT), and ashing.
Authors
Gittens SA; Wohl GR; Zernicke RF; Matyas JR; Morley P; Uludag H
Journal
Journal of Pharmacy & Pharmaceutical Sciences, Vol. 7, No. 1, pp. 27–37
ISSN
1482-1826