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Encephalitis with refractory seizures, status...
Journal article

Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a case series, characterisation of the antigen, and analysis of the effects of antibodies

Abstract

BACKGROUND: Increasing evidence suggests that seizures and status epilepticus can be immune-mediated. We aimed to describe the clinical features of a new epileptic disorder, and to establish the target antigen and the effects of patients' antibodies on neuronal cultures. METHODS: In this observational study, we selected serum and CSF samples for antigen characterisation from 140 patients with encephalitis, seizures or status epilepticus, and …

Authors

Petit-Pedrol M; Armangue T; Peng X; Bataller L; Cellucci T; Davis R; McCracken L; Martinez-Hernandez E; Mason WP; Kruer MC

Journal

The Lancet Neurology, Vol. 13, No. 3, pp. 276–286

Publisher

Elsevier

Publication Date

3 2014

DOI

10.1016/s1474-4422(13)70299-0

ISSN

1474-4422