selected scholarly activity
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chapters
- Colorectal and Anal Tumors. Pediatric Oncology. 319-333. 2017
- PTEN and the Cowden and Bannayan–Riley–Ruvalcaba Syndromes. 580-588. 2008
- PTEN and Cowden Syndrome. 95-110. 2007
- Adjuvant Therapy for completely resected stage II Colon Cancer. Clinical Respiratory Journal.
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conferences
- Topographical incidence and survival analysis of gastrointestinal tract cancer in adolescent and young adults compared with older adults in the United States.. Journal of Clinical Oncology. 545-545. 2017
- Reasons for delay in time to initiation of adjuvant chemotherapy (TTAC) for colon cancer (CC): Analysis from six academic centers in Ontario, Canada.. Journal of Clinical Oncology. 6541-6541. 2016
- Abstract 1154: Serum and urine markers of metabolic dysfunction in colorectal cancer: A pilot study. Cancer Research. 1154-1154. 2015
- Blood and urine markers of metabolic dysfunction in colorectal cancer: a pilot study.. Journal of Clinical Oncology. e14611-e14611. 2015
- Reasons for delay in time to initiation of adjuvant chemotherapy for colon cancer: A multi-institution study.. Journal of Clinical Oncology. e14504-e14504. 2014
- A case series of Lynch syndrome-associated breast cancer.. Journal of Clinical Oncology. 432-432. 2014
- Rapid assessment of frailty prior to treatment of elderly colorectal cancer patients.. Journal of Clinical Oncology. 2013
- Rapid assessment of frailty prior to treatment of elderly colorectal cancer patients.. Journal of Clinical Oncology. e20522-e20522. 2013
- Classification of a VUS in MLH1 using a combination of family segregation studies and protein biochemistry.. Journal of Clinical Oncology. 342-342. 2013
- PATIENT FACTORS INVOLVED IN REFERRAL FOR LYNCH SYNDROME. Annals of Oncology. 91-91. 2012
- Utility of the Edmonton Frail Scale (EFS) in identifying frail elderly patients during treatment of colorectal cancer (CRC). Journal of Clinical Oncology. 2012
- Utility of the Edmonton Frail Scale (EFS) in identifying frail elderly patients during treatment of colorectal cancer (CRC).. Journal of Clinical Oncology. 2012
- PTEN is a biomarker for endometrial glandular neoplasms that detects histologically occult precursors ("Latent precancers") years in advance of clinically diagnosible disease. Laboratory Investigation. 214A-214A. 2008
- PTEN is a biomarker for endometrial glandular neoplasms that detects histologically occult precursors ("latent precancers") years in advance of clinically diagnosible disease. Modern Pathology. 214A-214A. 2008
- A phase II study of triapine in combination with gemcitabine in advanced pancreatic carcinoma: A Princess Margaret Hospital phase II consortium trial.. Journal of Clinical Oncology. 331S-331S. 2005
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journal articles
- Sirolimus for vascular anomalies associated with PTEN hamartoma tumor syndrome.. Pediatric Blood and Cancer. e31282. 2024
- Four-year overall survival update from the phase III HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma. Annals of Oncology. 35:448-457. 2024
- Pan-Canadian consensus recommendations for GIST management in high- and low-throughput centres across Canada. Therapeutic Advances in Medical Oncology. 16. 2024
- Desmoplastic small round cell tumor involving the uterine cervix: The first reported case in the literature, and brief review of gynecologic presentations. Gynecologic Oncology Reports. 44:101079-101079. 2022
- Regional Therapies for Colorectal Liver Metastases: Systematic Review and Clinical Practice Guideline. Clinical Colorectal Cancer. 20:20-28. 2021
- Genomic and Clinical Correlates of Adrenocortical Carcinoma in an Adult Patient with Li-Fraumeni Syndrome: A Case Report. Current Oncology. 28:226-232. 2020
- ATM whole gene deletion in an Italian family with hereditary pancreatic cancer: Challenges to cancer risk prediction associated with an 11q22.3 microdeletion. Cancer genetics. 240:1-4. 2020
- Predictors of mammographic density among women with a strong family history of breast cancer. BMC Cancer. 19:631. 2019
- Colorectal cancer in adolescents and young adults: Defining a growing threat. Pediatric Blood and Cancer. 66:e27941. 2019
- The Surveillance After Extremity Tumor Surgery (SAFETY) trial: protocol for a pilot study to determine the feasibility of a multi-centre randomised controlled trial. BMJ Open. 9:e029054-e029054. 2019
- SDH-deficient renal cell carcinoma – clinical, pathologic and genetic correlates: a case report. BMC Urology. 18:109. 2018
- Role of the status of the mesorectal fascia in the selection of patients with rectal cancer for preoperative radiation therapy: a retrospective cohort study. Canadian Journal of Surgery. 61:332-338. 2018
- Role of the status of the mesorectal fascia in the selection of patients with rectal cancer for preoperative radiation therapy: a retrospective cohort study.. Canadian Journal of Surgery. 61:332-338. 2018
- Serum osteoprotegerin levels and mammographic density among high-risk women. Cancer Causes and Control. 29:507-517. 2018
- Quality of preoperative pelvic computed tomography (CT) and magnetic resonance imaging (MRI) for rectal cancer in a region in Ontario: A retrospective population‐based study. Journal of Surgical Oncology. 117:1038-1042. 2018
- Association between the Lynch syndrome gene MSH2 and breast cancer susceptibility in a Canadian familial cancer registry. Journal of Medical Genetics. 54:742-746. 2017
- Systemic Therapy in Incurable Gastroenteropancreatic Neuroendocrine Tumours: A Clinical Practice Guideline. Current Oncology. 24:249-255. 2017
- Utility of the Edmonton Frail Scale in identifying frail elderly patients during treatment of colorectal cancer. Journal of Gastrointestinal Oncology. 8:32-38. 2017
- Targeted metabolomics in colorectal cancer: a strategic approach using standardized laboratory tests of the blood and urine. Hypoxic Signaling. Volume 5:61-66. 2017
- Randomized phase II study of modified FOLFOX-6 in combination with ramucirumab or icrucumab as second-line therapy in patients with metastatic colorectal cancer after disease progression on first-line irinotecan-based therapy. Annals of Oncology. 27:2216-2224. 2016
- Thrombotic events in metastatic colorectal cancer patients treated with leucovorin, fluorouracil and irinotican (FOLFIRI) plus bevacizumab.. Journal of Gastrointestinal Oncology. 6:274-279. 2015
- Prospective study of high-risk, BRCA1/2-mutation negative women: the ‘negative study’. BMC Cancer. 14:221. 2014
- Reasons for Delay in Time to Initiation of Adjuvant Chemotherapy for Colon Cancer: a Multi-Institution Study. Annals of Oncology. 25:iv198-iv198. 2014
- Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer. Breast Cancer Research and Treatment. 146:447-450. 2014
- Epidermal Growth Factor Receptor: Pathway, Therapies, and Pipeline. Clinical Therapeutics. 35:1282-1303. 2013
- Accelerated muscle and adipose tissue loss may predict survival in pancreatic cancer patients: the relationship with diabetes and anaemia. British Journal of Nutrition. 109:302-312. 2013
- BRCA2 Variants and cardiovascular disease in a multi-ethnic study. BMC Medical Genomics. 13:56. 2012
- Fertility Risk Discussions in Young Patients Diagnosed with Colorectal Cancer. Current Oncology. 19:155-159. 2012
- P-0215 Patient Factors Involved in Referral for Lynch Syndrome. Annals of Oncology. 23:iv91-iv91. 2012
- Utility of the Edmonton Frail Scale (EFS) in identifying frail elderly patients during treatment of colorectal cancer (CRC).. Journal of Clinical Oncology. 30:e14001-e14001. 2012
- Is Colon Cancer Survival Influenced by Tumor Location?. Journal of Clinical Oncology. 30:1732-1733. 2012
- Chemotherapy for colorectal cancer. The Lancet Oncology. 13:e3-e4. 2012
- Declining incidence of breast cancer after decreased use of hormone-replacement therapy: magnitude and time lags in different countries. Journal of Epidemiology and Community Health. 66:1-7. 2012
- Frequency of fertility discussions among young patients diagnosed with colorectal cancer.. Journal of Clinical Oncology. 29:e19735-e19735. 2011
- Colorectal Cancer in Young Adults. Seminars in Oncology. 36:439-450. 2009
- Germline Mutations and Variants in the Succinate Dehydrogenase Genes in Cowden and Cowden-like Syndromes. American Journal of Human Genetics. 83:261-268. 2008
- Multiple Tumors in a Child with Germ-Line Mutations inTP53andPTEN. New England Journal of Medicine. 359:537-539. 2008
- Cowden Syndrome. Seminars in Oncology. 34:428-434. 2007
- Cowden Syndrome–Affected Patients with PTEN Promoter Mutations Demonstrate Abnormal Protein Translation. American Journal of Human Genetics. 81:756-767. 2007
- Germline mutations in PTEN and SDHC in a woman with epithelial thyroid cancer and carotid paraganglioma. Nature Reviews Clinical Oncology. 4:608-612. 2007
- Hamartomatous polyposis syndromes. Nature Reviews Gastroenterology and Hepatology. 4:492-502. 2007
- Severe TMD/AMKL with GATA1 mutation in a stillborn fetus with Down syndrome. Nature Reviews Clinical Oncology. 4:433-438. 2007
- Comparative genomic and functional analyses reveal a novel cis-acting PTEN regulatory element as a highly conserved functional E-box motif deleted in Cowden syndrome. Human Molecular Genetics. 16:1058-1071. 2007
- Cancer phenomics: RET and PTEN as illustrative models. Nature Reviews Cancer. 7:35-45. 2007
- Predicting response to EGFR-tyrosine kinase inhibitors among diverse ancestries: Just way too polymorphic. Cancer Biology and Therapy. 6:112-115. 2007
- A phase II study of triapine in combination with gemcitabine in advanced pancreatic carcinoma: A Princess Margaret Hospital Phase II Consortium Trial. Journal of Clinical Oncology. 23:4093-4093. 2005
- Quetiapine fumarate overdose: Clinical and pharmacokinetic lessons from extreme conditions. Clinical Pharmacology and Therapeutics. 68:92-97. 2000