selected scholarly activity
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chapters
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conferences
- Effects of Hyperglycemia on Endothelial Activation and Early Atherosclerotic Plaque Development. Atherosclerosis Plus. 86-87. 2018
- Investigating the Molecular Mechanisms by Which Sex Hormones Modulate Beta Cell Function and Diabetes Associated-Atherosclerosis. Atherosclerosis Plus. 88-88. 2018
- The Role of GSK3α/β in Macrophage Polarization and Function. Atherosclerosis Plus. 99-100. 2018
- Androgen-deprivation therapy-induced atherosclerosis in prostate cancer: Differences between GnRH-agonist and antagonist. Atherosclerosis. e87-e87. 2016
- Examining the hexosamine biosynthesis pathway in hyperglycemia-induced accelerated atherosclerosis. Journal of Thrombosis and Haemostasis. 95-95. 2015
- Hyperglycaemic apolipoprotein-E deficient mice have accelerated atherosclerosis and aberrant vasa vasorum neovascularization. Journal of Thrombosis and Haemostasis. 791-791. 2015
- A Metabolic Approach to Examining the Hexosamine Biosynthetic Pathway and Its Role in the Development of Diabetes-Associated Atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology. 2014
- Androgen Deprivation Therapy-Induced Weight Gain and Atherosclerosis in Prostate Cancer: Differences Between Orchiectomy, GnRH Agonist and Antagonist. Arteriosclerosis, Thrombosis and Vascular Biology. 2014
- Hyperglycemia Increases Diet-Induced Coronary Artery Disease and Myocardial Infarction in SRBI Knockout ApoE-Hypomorphic Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 2014
- Investigating the Role of the Hexosamine Biosynthesis Pathway in Diabetic Atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology. 2014
- PKR-Like Endoplasmic Reticulum Kinase and Glycogen Synthase Kinase-3 alpha/beta Signaling Regulates Endoplasmic Reticulum Stress-Induced Foam Cell Formation. Arteriosclerosis, Thrombosis and Vascular Biology. 2014
- MP24-11 GNRH ANTAGONISTS ASSOCIATE WITH LESS WEIGHT GAIN AND MILDER CHARACTERISTICS OF THE METABOLIC SYNDROME AND ATHEROSCLEROSIS COMPARED TO SURGICAL CASTRATION AND GNRH ANALOGUES IN PRE-CLINICAL ANIMAL MODEL. Investigative Urology. E263-E263. 2014
- Pkr- like endoplasmic reticulum kinase (PERK) and glycogen synthase kinase-3 alpha/beta signaling regulate atherosclerosis development. The FASEB Journal. 2014
- Pkr‐like endoplasmic reticulum kinase (PERK) and glycogen synthase kinase‐3α/β signaling regulate atherosclerosis development (278.5). The FASEB Journal. 2014
- The role of FSH in castration-induced adipogenesis and cardiovascular diseases: Highlighting differences between orchiectomy, GNRH agonists, and antagonists.. Journal of Clinical Oncology. 191-191. 2014
- Effect of Diabetes on Atherosclerosis and Myocardial Infarction in SR-BI-/-APOE Hypomorphic Mice. Canadian Journal of Cardiology. S175-S176. 2013
- Examining the Hexosamine Biosynthetic Pathway and Its Role in the Development of Diabetes-Associated Atherosclerosis: A Metabolomic Approach. Canadian Journal of Cardiology. S169-S169. 2013
- Investigating the Role of ER Stress and GSK-3 in the Osteogenic Differentiation of the Movas Cell Line. Canadian Journal of Cardiology. S164-S164. 2013
- Investigating the Role of Glycogen Synthase Kinase (GSK)-3α/β in Pro-Atherogenic Endoplasmic Reticulum (ER) Stress Signaling. Canadian Journal of Cardiology. S268-S268. 2013
- Investigating the Role of the Hexosamine Biosynthesis Pathway in Diabetic Atherosclerosis. Canadian Journal of Cardiology. S254-S254. 2013
- Examining the Role of Endoplasmic Reticulum Stress Induced Glycogen Synthase Kinasea-3 alpha/beta in Accelerated Atherosclerosis. Circulation. 2012
- 032 Investigating the Role of the Hexosamine Biosynthesis Pathway in Diabetic Atherosclerosis. Canadian Journal of Cardiology. S96-S97. 2012
- 419 Investigating the Role of Glycogen Synthase Kinase (GSK)-3 in Pro-Atherogenic Endoplasmic Reticulum (ER) Stress Signaling. Canadian Journal of Cardiology. S256-S257. 2012
- 716 Leptin Promotes the Osteoblast Differentiation and Mineralization of Primary Cultures of Vascular Smooth Muscle Cells by Regulating GSK-3β. Canadian Journal of Cardiology. S373-S374. 2012
- IS ACCELERATED ATHEROSCLEROSIS A MICROVASCULAR COMPLICATION OF DIABETES?. Canadian Journal of Cardiology. S95-S96. 2012
- Discovery of novel L-glutamine:D-fructose-6-phosphate amidotransferase (GFAT) inhibitors via a high-throughput screening campaign. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2012
- 074 Glucosamine-supplementation promotes ER stress and accelerated atherogenesis in APOE-deficient mice. Canadian Journal of Cardiology. S88-S88. 2011
- 081 Analysis and characterization of atherosclerosis in LDLR/GSK3α double knockout mice: Examining the role of glycogen synthase kinase 3 in the progression of atherosclerosis. Canadian Journal of Cardiology. S91-S91. 2011
- 485 Endoplasmic Reticulum stress and Glycogen Synthase Kinase-3 beta activation in apolipoprotein e-deficient mouse models of accelerated atherosclerosis. Canadian Journal of Cardiology. S237-S238. 2011
- GLUCOSAMINE-SUPPLEMENTATION PROMOTES ER STRESS AND ACCELERATED ATHEROGENESIS IN APOE-DEFICIENT MICE. Canadian Journal of Cardiology. 120D-120D. 2010
- INVESTIGATING THE PRO-ATHEROGENIC POTENTIAL OF CHRONIC HYPERGLYCAEMIA: IS DIABETIC ATHEROSCLEROSIS A MICROVASCULAR COMPLICATION?. Canadian Journal of Cardiology. 119D-119D. 2010
- INVESTIGATING THE ROLE OF GLYCOGEN SYNTHASE KINASE (GSK)-3 IN DIABETIC ATHEROSCLEROSIS. Canadian Journal of Cardiology. 141D-142D. 2010
- The effect of leptin on vascular calcification in apolipoprotein E - deficient mice. Journal of Thrombosis and Haemostasis. 906-906. 2009
- An oral glucose challenge induces endoplasmic reticulum stress in circulating blood cells and vascular tissue: A possible mechanism linking postprandial hyperglycemia to cardiovascular risk. Diabetes. A73-A73. 2008
- ENDOPLASMIC RETICULUM STRESS INCREASES PLASMA MEMBRANE CHOLESTEROL CONTENT AND AFFECTS NITRIC OXIDE PRODUCTION IN ENDOTHELIAL CELLS. Atherosclerosis Plus. 58-58. 2008
- Dietary supplementation with sodium valproate attenuates lesion development in hyperglycemic apolipoprotein E-deficient mice. Circulation. 268-268. 2007
- A molecular mechanism linking diabetes mellitus to the development of atherosclerosis. Canadian Journal of Cardiology. 181C-181C. 2007
- Mechanisms linking diabetes mellitus to the development of atherosclerosis: a role for endoplasmic reticulum stress and glycogen synthase kinase-3This paper is one of a selection of papers published in this Special Issue, entitled Young Investigator's Forum.. Canadian Journal of Physiology and Pharmacology. 39-48. 2006
- Glucosamine-induced endoplasmic reticulum (ER) stress promotes cellular dysfunction associated with atherogenesis. Diabetes. A478-A478. 2003
- Homocysteine enhances cholesterol biosynthesis in cultured human smooth muscle cells and hepatocytes.. Blood. 449A-449A. 1999
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journal articles
- Myeloid GSK3α Deficiency Reduces Lesional Inflammation and Neovascularization during Atherosclerotic Progression.. International Journal of Molecular Sciences. 25:10897. 2024
- Investigating the effects of testosterone and dihydrotestosterone on atherogenesis in normoglycemic and hyperglycemic ApoE-/- mice. Atherosclerosis. 395:118305. 2024
- Understanding One Half of the Sex Difference Equation. American Journal of Pathology. 194:551-561. 2024
- Investigating the Role of 17-Beta Estradiol in the Regulation of the Unfolded Protein Response (UPR) in Pancreatic Beta Cells. International Journal of Molecular Sciences. 25:1816-1816. 2024
- Investigating the Effects of Sex Hormones on Macrophage Polarization. International Journal of Molecular Sciences. 25:951-951. 2024
- OC 16.1 The Role of Endothelial Glycogen Synthase Kinase (GSK)-3α in Hyperglycemia-Induced Endothelial Activation and Atherosclerosis. Research and Practice in Thrombosis and Haemostasis. 7:100298-100298. 2023
- PB1426 Studies of Streptozotocin-Induced Hyperglycemia on the Host Response to Sepsis. Research and Practice in Thrombosis and Haemostasis. 7:101693-101693. 2023
- The Implications of Cannabinoid-Induced Metabolic Dysregulation for Cellular Differentiation and Growth. International Journal of Molecular Sciences. 24:11003-11003. 2023
- PCSK9 facilitates melanoma pathogenesis via a network regulating tumor immunity. Journal of Experimental and Clinical Cancer Research. 42:2. 2023
- The Effects of Hyperglycemia on Early Endothelial Activation and the Initiation of Atherosclerosis. American Journal of Pathology. 193:121-133. 2023
- Investigating the Role of Endothelial Glycogen Synthase Kinase3α/β in Atherogenesis in Low Density Lipoprotein Receptor Knockout Mice. International Journal of Molecular Sciences. 23:14780-14780. 2022
- Correction: Protective effect of pharmacological castration on metabolic perturbations and cardiovascular disease in the hyperglycemic male ApoE−/−:Ins2+/Akita mouse model. Prostate Cancer and Prostatic Diseases. 25:596-596. 2022
- Investigating the protective effects of estrogen on β-cell health and the progression of hyperglycemia-induced atherosclerosis. American Journal of Physiology - Endocrinology and Metabolism. 323:E254-E266. 2022
- Deletion of Macrophage-Specific Glycogen Synthase Kinase (GSK)-3α Promotes Atherosclerotic Regression in Ldlr−/− Mice. International Journal of Molecular Sciences. 23:9293-9293. 2022
- Insight into genetic, biological, and environmental determinants of sexual-dimorphism in type 2 diabetes and glucose-related traits. Frontiers in Cardiovascular Medicine. 9:964743. 2022
- Salsalate reduces atherosclerosis through AMPKβ1 in mice. Molecular Metabolism. 53:101321-101321. 2021
- The Effect of Testosterone on Cardiovascular Disease and Cardiovascular Risk Factors in Men: A Review of Clinical and Preclinical Data. CJC OPEN. 3:1238-1248. 2021
- The Role of Estrogen in Insulin Resistance. American Journal of Pathology. 191:1490-1498. 2021
- Biomarkers of coagulation, endothelial function, and fibrinolysis in critically ill patients with COVID‐19: A single‐center prospective longitudinal study. Journal of Thrombosis and Haemostasis. 19:1546-1557. 2021
- Protective effect of pharmacological castration on metabolic perturbations and cardiovascular disease in the hyperglycemic male ApoE−/−:Ins2+/Akita mouse model. Prostate Cancer and Prostatic Diseases. 24:389-397. 2021
- Macrophage Function and the Role of GSK3. International Journal of Molecular Sciences. 22:2206-2206. 2021
- Characterizing the Role of Glycogen Synthase Kinase-3α/β in Macrophage Polarization and the Regulation of Pro-Atherogenic Pathways in Cultured Ldlr-/- Macrophages. Frontiers in Immunology. 12:676752. 2021
- Characterization of Retinal Microvascular Complications and the Effects of Endoplasmic Reticulum Stress in Mouse Models of Diabetic Atherosclerosis. Investigative Ophthalmology and Visual Science. 61:49-49. 2020
- Role of Estrogen in Type 1 and Type 2 Diabetes Mellitus: A Review of Clinical and Preclinical Data. Canadian Journal of Diabetes. 44:448-452. 2020
- Dysglycemia and the Density of the Coronary Vasa Vasorum. Diabetes Care. 42:980-982. 2019
- Untargeted Metabolomics in the Discovery of Novel Biomarkers and Therapeutic Targets for Atherosclerotic Cardiovascular Diseases. Cardiovascular and Hematological Disorders - Drug Targets. 18:166-175. 2018
- Evidence of extensive atherosclerosis, coronary artery disease and myocardial infarction in the ApoE−/−:Ins2 mouse fed a western diet. Atherosclerosis. 275:88-96. 2018
- Glycosphingolipids promote pro-atherogenic pathways in the pathogenesis of hyperglycemia-induced accelerated atherosclerosis. Metabolomics. 14:92. 2018
- Extensive Atherosclerosis, Coronary Artery Disease and Myocardial Infarction in the ApoE-/-:Ins2+/Akita Mouse Fed a Diet Rich in Fat. Atherosclerosis Plus. 32:104-105. 2018
- The Role of Endoplasmic Reticulum Stress-Glycogen Synthase Kinase-3 Signaling in Atherogenesis. International Journal of Molecular Sciences. 19:1607-1607. 2018
- 4-phenylbutyrate and valproate treatment attenuates the progression of atherosclerosis and stabilizes existing plaques. Atherosclerosis. 266:103-112. 2017
- Glucosamine induces ER stress by disrupting lipid-linked oligosaccharide biosynthesis andN-linked protein glycosylation. American Journal of Physiology - Endocrinology and Metabolism. 312:E48-E57. 2017
- Comprehensive Plasma Metabolomic Analyses of Atherosclerotic Progression Reveal Alterations in Glycerophospholipid and Sphingolipid Metabolism in Apolipoprotein E-deficient Mice. Scientific Reports. 6:35037. 2016
- COMPREHENSIVE METABOLOMIC ANALYSES REVEAL ALTERATIONS IN GLYCEROPHOSPHOLIPID AND SPHINGOLIPID METABOLISM DURING THE PATHOGENESIS AND PROGRESSION OF ATHEROSCLEROSIS. Canadian Journal of Cardiology. 32:S239-S239. 2016
- INVESTIGATING THE MOLECULAR MECHANISMS BY WHICH SEX HORMONES MODULATE BETA CELL HEALTH IN A MODEL OF HYPERGLYCEMIA-INDUCED ATHEROSCLEROSIS. Canadian Journal of Cardiology. 32:S77-S78. 2016
- THE ROLE OF ENDOPLASMIC RETICULUM STRESS AND GLYCOGEN SYNTHASE KINASE-3α/β IN ATHEROSCLEROTIC PROGRESSION AND REGRESSION. Canadian Journal of Cardiology. 32:S238-S238. 2016
- Mitochondrial ROS versus ER ROS: Which Comes First in Myocardial Calcium Dysregulation?. Frontiers in Cardiovascular Medicine. 3:36. 2016
- Sex-Specific Differences in an ApoE−/−:Ins2+/Akita Mouse Model of Accelerated Atherosclerosis. American Journal of Pathology. 186:67-77. 2016
- THE ROLE OF ENDOPLASMIC RETICULUM STRESS AND GLYCOGEN SYNTHASE KINASE-3α/β IN ATHEROSCLEROTIC PROGRESSION AND REGRESSION. Canadian Journal of Cardiology. 31:S112-S113. 2015
- Abstract 19: Deletion of Myeloid GSK3α Attenuates Atherosclerosis and Promotes an M2 Macrophage Phenotype. Arteriosclerosis, Thrombosis and Vascular Biology. 35. 2015
- Abstract 559: FTY720 Protects Against Diet Induced Coronary Artery Disease and Myocardial Infarction in Diabetic SR-B1-/- ApoE-Hypomorphic Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 35. 2015
- Deletion of Myeloid GSK3α Attenuates Atherosclerosis and Promotes an M2 Macrophage Phenotype. Arteriosclerosis, Thrombosis and Vascular Biology. 35:1113-1122. 2015
- Glycogen Synthase Kinase 3α Deficiency Attenuates Atherosclerosis and Hepatic Steatosis in High Fat Diet–Fed Low Density Lipoprotein Receptor–Deficient Mice. American Journal of Pathology. 184:3394-3404. 2014
- GnRH antagonist associates with less adiposity and reduced characteristics of metabolic syndrome and atherosclerosis compared with orchiectomy and GnRH agonist in a preclinical mouse model1Contributed equally and share first authorship.. Urologic Oncology: Seminars and Original Investigations. 32:1126-1134. 2014
- Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation. Journal of Lipid Research. 55:2320-2333. 2014
- GENDER SPECIFIC DIFFERENCES IN A NEW APOE-/-:INS2+/AKITA MOUSE MODEL OF HYPERGLYCEMIA-INDUCED ATHEROSCLEROSIS. Canadian Journal of Cardiology. 30:S325-S325. 2014
- HYPERGLYCAEMIC APOLIPOPROTEIN-E DEFICIENT MICE HAVE ACCELERATED ATHEROSCLEROSIS AND ABERRANT VASA VASORUM NEOVASCULARIZATION. Canadian Journal of Cardiology. 30:S269-S270. 2014
- METABOLOMIC INVESTIGATION OF THE HEXOSAMINE BIOSYNTHESIS PATHWAY IN HYPERGLYCEMIA-INDUCED ACCELERATED ATHEROSCLEROSIS. Canadian Journal of Cardiology. 30:S271-S271. 2014
- PKR-LIKE ENDOPLASMIC RETICULUM KINASE (PERK) AND GLYCOGEN SYNTHASE KINASE (GSK)-3α/β SIGNALING REGULATE ATHEROSCLEROSIS DEVELOPMENT. Canadian Journal of Cardiology. 30:S325-S326. 2014
- Abstract 251: Investigating the Role of the Hexosamine Biosynthesis Pathway in Diabetic Atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 409: Is Accelerated Atherosclerosis a Microvascular Complication of Diabetes?. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 596: Androgen Deprivation Therapy--Induced Weight Gain and Atherosclerosis in Prostate Cancer: Differences Between Orchiectomy, GnRH Agonist and Antagonist. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 647: Hyperglycemia Increases Diet-Induced Coronary Artery Disease and Myocardial Infarction in SRBI Knockout ApoE-Hypomorphic Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 659: PKR-Like Endoplasmic Reticulum Kinase and Glycogen Synthase Kinase-3α/ß Signaling Regulates Endoplasmic Reticulum Stress-Induced Foam Cell Formation. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Abstract 670: A Metabolic Approach to Examining the Hexosamine Biosynthetic Pathway and Its Role in the Development of Diabetes-Associated Atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- 308 The role of FSH in castration-induced weight gain and cardiovascular disease: Differences between orchiectomy, GnRH agonists and antagonists. European Urology Open Science. 13:e308-e308. 2014
- Oral glucosamine sulfate supplementation does not induce endoplasmic reticulum stress or activate the unfolded protein response in circulating leukocytes of human subjects. Canadian Journal of Physiology and Pharmacology. 92:285-291. 2014
- Oxidative Stress and Aging Diseases. Oxidative Medicine and Cellular Longevity. 2014:1-2. 2014
- Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus. Journal of Visualized Experiments. 50933. 2013
- Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1833:2293-2301. 2013
- Molecular Mechanisms Linking Diabetes to the Accelerated Development of Atherosclerosis. Canadian Journal of Diabetes. 37:345-350. 2013
- Dysglycaemia, vasculopenia, and the chronic consequences of diabetes. The Lancet Diabetes and Endocrinology. 1:71-78. 2013
- The Development and Progression of Atherosclerosis: Evidence supporting a Role for Endoplasmic Reticulum (ER) Stress Signaling. Cardiovascular and Hematological Disorders - Drug Targets. 13:158-164. 2013
- Abstract 79: Examining the Role of Endoplasmic Reticulum Stress Induced Glycogen Synthase Kinase-3a/ß in Accelerated Atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology. 33. 2013
- Hyperglycaemia is associated with impaired vasa vasorum neovascularization and accelerated atherosclerosis in apolipoprotein-E deficient mice. Atherosclerosis. 227:250-258. 2013
- 030 Is Accelerated Atherosclerosis a Microvascular Complication of Diabetes?. Canadian Journal of Cardiology. 28:S95-S96. 2012
- Leptin promotes osteoblast differentiation and mineralization of primary cultures of vascular smooth muscle cells by inhibiting glycogen synthase kinase (GSK)-3β. Biochemical and Biophysical Research Communications. 425:924-930. 2012
- Abstract 300: Leptin Promotes the Osteoblast Differentiation and Mineralization of Primary Cultures of Vascular Smooth Muscle Cells by Regulating GSK-3β. Arteriosclerosis, Thrombosis and Vascular Biology. 32. 2012
- Metabolic Syndrome and Acute Hyperglycemia Are Associated With Endoplasmic Reticulum Stress in Human Mononuclear Cells. Obesity. 20:748-755. 2012
- Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology. 32:82-91. 2012
- The Role of Glucosamine-Induced ER Stress in Diabetic Atherogenesis. Journal of Diabetes Research. 2012:1-11. 2012
- Glucosamine-supplementation promotes endoplasmic reticulum stress, hepatic steatosis and accelerated atherogenesis in apoE−/− mice. Atherosclerosis. 219:134-140. 2011
- Interleukin‐15 Contributes to the Regulation of Murine Adipose Tissue and Human Adipocytes. Obesity. 18:1601-1607. 2010
- Diabetes, Hyperglycemia and Accelerated Atherosclerosis: Evidence Supporting a Role for Endoplasmic Reticulum (ER) Stress Signaling. Cardiovascular and Hematological Disorders - Drug Targets. 10:151-157. 2010
- Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells. American Journal of Physiology - Endocrinology and Metabolism. 298:E499-E511. 2010
- Effect of Leptin on Vascular Calcification in Apolipoprotein E–Deficient Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 29:2069-2075. 2009
- Evidence Supporting a Role for Endoplasmic Reticulum Stress in the Development of Atherosclerosis in a Hyperglycaemic Mouse Model. Antioxidants and Redox Signaling. 11:2289-2298. 2009
- Effects of hyperglycemia on the modulation of vascular function by perivascular adipose tissue. Journal of Hypertension. 27:118-131. 2009
- Valproate Attenuates Accelerated Atherosclerosis in Hyperglycemic ApoE-Deficient Mice. American Journal of Pathology. 174:330-342. 2009
- Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice. The FASEB Journal. 22:2569-2578. 2008
- An ESI‐MS/MS Method for Screening of Small‐Molecule Mixtures against Glycogen Synthase Kinase‐3β (GSK‐3β). ChemBioChem. 9:1065-1073. 2008
- Metabolic Syndrome and Acute Hyperglycemia Promote Endoplasmic Reticulum Stress in Circulating Human Mononuclear Cells. Canadian Journal of Diabetes. 32:312-312. 2008
- Abstract 1312: Dietary Supplementation With Sodium Valproate Attenuates Lesion Development In Hyperglycemic Apolipoprotein E-deficient Mice. Circulation. 116. 2007
- Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition. Bioorganic and Medicinal Chemistry Letters. 17:4491-4494. 2007
- Diabetes and cardiovascular disease: explaining the relationship.. Reviews in Cardiovascular Medicine. 8:145-153. 2007
- Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2. International Journal of Biochemistry and Cell Biology. 39:1843-1851. 2007
- Glucosamine-Induced Endoplasmic Reticulum Dysfunction Is Associated With Accelerated Atherosclerosis in a Hyperglycemic Mouse Model. Diabetes. 55:93-101. 2006
- Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3. Journal of Cell Science. 118:89-99. 2005
- Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds. Bioorganic and Medicinal Chemistry Letters. 14:5465-5467. 2004
- Association of Multiple Cellular Stress Pathways With Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-Deficient Mice. Circulation. 110:207-213. 2004
- Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease. Cell Death and Differentiation. 11:S56-S64. 2004
- POTENTIAL ROLE FOR GLYCOGEN SYNTHASE KINASE (GSK)-3 IN ENDOPLASMIC RETICULUM (ER) STRESS-INDUCED ATHEROSCLEROSIS. Cardiovascular Pathology. 13:29-29. 2004
- Hyperhomocysteinemia and its role in the development of atherosclerosis. Clinical Biochemistry. 36:431-441. 2003
- TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia. Journal of Biological Chemistry. 278:30317-30327. 2003
- Overexpression of the 78-kDa Glucose-regulated Protein/Immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity. Journal of Biological Chemistry. 278:17438-17447. 2003
- Identification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton. Journal of Biological Chemistry. 277:47106-47113. 2002
- Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. Journal of Clinical Investigation. 107:1263-1273. 2001
- Controlling Gene Expression in Living Cells Through Small Molecule-RNA Interactions. Science. 282:296-298. 1998
- A non-canonical base pair within the human immunodeficiency virus Rev-responsive element is involved in both Rev and small molecule recognition. Cell Chemical Biology. 3:129-137. 1996
- An unusual cellular factor potentiates protein-DNA complex assembly between Oct-1 and Vmw65.. Journal of Biological Chemistry. 268:1272-1278. 1993
- Synthesis of the herpes simplex virus type 1 trans-activator Vmw65 in insect cells using a baculovirus vector. Molecular and Cellular Biochemistry. 94:45-52. 1990
- Enhanced infectivity of herpes simplex virus type 1 viral DNA in a cell line expressing the trans-inducing factor Vmw65. Journal of Virology. 64:984-991. 1990
- Identification of a domain of the herpes simplex virus trans-activator Vmw65 required for protein-DNA complex formation through the use of protein A fusion proteins. Journal of Virology. 63:5509-5513. 1989
- Mutational analysis of the herpes simplex virus trans-inducing factor Vmw65. Gene. 75:213-224. 1989
- Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus. Journal of Visualized Experiments.
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preprints
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theses
- COMPREHENSIVE METABOLOMIC ANALYSIS OF DIABETIC ATHEROSCLEROSIS. Canadian Journal of Cardiology. 2015