Extracellular Signal-Regulated MAP Kinases Concept

subject area of

• IRAK-4 Mutation (Q293X): Rapid Detection and Characterization of Defective Post-Transcriptional TLR/IL-1R Responses in Human Myeloid and Non-Myeloid Cells  Academic Article
• A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leukemia: a NCIC (National Cancer Institute of Canada) Clinical Trials Group Study  Academic Article
• A review of the effects of statins in systemic sclerosis  Academic Article
• Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells  Academic Article
• Anti-Inflammatory Effects of Tanshinone IIA on Atherosclerostic Vessels of Ovariectomized ApoE-/- Mice are Mediated by Estrogen Receptor Activation and Through the ERK Signaling Pathway  Academic Article
• Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma  Academic Article
• EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)  Academic Article
• ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function  Academic Article
• ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response.  Academic Article
• Exposure to cigarette smoke suppresses IL-15 generation and its regulatory NK cell functions in poly I:C-augmented human PBMCs  Academic Article
• Extracellular Signal-Regulated Kinases Modulate DNA Damage Response - A Contributing Factor to Using MEK Inhibitors in Cancer Therapy  Academic Article
• G-protein-coupled receptor independent, immunomodulatory properties of chemokine CXCL9  Academic Article
• Heritable pathologic cardiac hypertrophy in adulthood is preceded by neonatal cardiac growth restriction  Academic Article
• High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells  Academic Article
• Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation  Academic Article
• Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS  Academic Article
• Investigation of FGFR2-IIIC Signaling via FGF-2 Ligand for Advancing GCT Stromal Cell Differentiation  Academic Article
• MAPping the kinase landscape of macrophage activation  Academic Article
• Mechanical Stretch-Induced Signal Transduction in Cultured Mesangial Cells  Academic Article
• Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment  Academic Article
• Mitogen-activated protein kinases Erk1/2 and p38 are required for maximal regulation of TIMP-1 by oncostatin M in murine fibroblasts  Academic Article
• Mutations inSYNGAP1Cause Intellectual Disability, Autism, and a Specific Form of Epilepsy by Inducing Haploinsufficiency  Academic Article
• Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1  Academic Article
• P2Y₂ Receptor Up-Regulation Induced by Guanosine or UTP in Rat Brain Cultured Astrocytes  Academic Article
• Pramanicin induces apoptosis in Jurkat leukemia cells: A role for JNK, p38 and caspase activation  Academic Article
• Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation  Academic Article
• Prostaglandin E₂ inhibits profibrotic function of human pulmonary fibroblasts by disrupting Ca²⁺ signaling  Academic Article
• Requirement and Redundancy of the Src Family Kinases Fyn and Lyn in Perforin-Dependent Killing of Cryptococcus neoformans by NK Cells  Academic Article
• Stretch-induced Raf-1 activation in mesangial cells requires actin cytoskeletal integrity  Academic Article
• Superoxide anion mediates angiotensin II-induced potentiation of contractile response to sympathetic stimulation  Academic Article
• Synthesis and Biological Activity of a Focused Library of Mitogen-activated Protein Kinase Phosphatase Inhibitors  Academic Article
• The GDNF Target Vsnl1 Marks the Ureteric Tip  Academic Article
• Uncoupling of Pro- and Anti-Inflammatory Properties of Staphylococcus aureus  Academic Article
• Upregulation of MMP-13 via Runx2 in the stromal cell of Giant Cell Tumor of Bone  Academic Article
• Visfatin activates eNOS via Akt and MAP kinases and improves endothelial cell function and angiogenesis in vitro and in vivo: translational implications for atherosclerosis  Academic Article