Journal article
Antibody-Dependent Transplacental Transfer of Malaria Blood-Stage Antigen Using a Human Ex Vivo Placental Perfusion Model
Abstract
Prenatal exposure to allergens or antigens released by infections during pregnancy can stimulate an immune response or induce immunoregulatory networks in the fetus affecting susceptibility to infection and disease later in life. How antigen crosses from the maternal to fetal environment is poorly understood. One hypothesis is that transplacental antigen transfer occurs as immune complexes, via receptor-mediated transport across the …
Authors
May K; Grube M; Malhotra I; Long CA; Singh S; Mandaliya K; Siegmund W; Fusch C; Schneider H; King CL
Journal
PLOS ONE, Vol. 4, No. 11,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0007986
ISSN
1932-6203