Journal article
An amantadine hydrochloride dosing program adjusted for renal function during an influenza outbreak in elderly institutionalized patients.
Abstract
OBJECTIVE: We tested the hypothesis that individualized dosing of amantadine hydrochloride, based upon a patient's creatinine clearance, would maintain efficacy against influenza A infection while reducing adverse reactions to the drug.
DESIGN: A prospective cohort study
Authors
Kolbe F; Sitar DS; Papaioannou A; Campbell G
Journal
Journal of Population Therapeutics and Clinical Pharmacology, Vol. 10, No. 3, pp. 119–122
Publication Date
2003
ISSN
1710-6222