Journal article
Effects of Ramipril on Coronary Events in High-Risk Persons
Abstract
BACKGROUND: In trials of patients with left ventricular dysfunction or heart failure, ACE inhibitor use was unexpectedly associated with reduced myocardial infarction (MI). Using the Heart Outcomes Prevention Evaluation (HOPE) trial data, we tested prospectively whether ramipril, an ACE inhibitor, could reduce coronary events and revascularization procedures among patients with normal left ventricular function.
METHODS AND RESULTS: In the HOPE …
Authors
Dagenais GR; Yusuf S; Bourassa MG; Yi Q; Bosch J; Lonn EM; Kouz S; Grover J; Investigators OBOTH
Journal
Circulation, Vol. 104, No. 5, pp. 522–526
Publisher
Wolters Kluwer
Publication Date
July 31, 2001
DOI
10.1161/hc3001.093502
ISSN
0009-7322