Characterization of health-related quality of life in heart failure patients with preserved versus low ejection fraction in CHARM Academic Article uri icon

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abstract

  • BACKGROUND: Limited comparative studies assessing the health-related quality of life (HRQL) in heart failure (HF) patients with preserved vs. low ejection fraction (LVEF) have been disparate. AIMS: The aims of this study were a) to characterize HRQL in a large population of HF patients with preserved and low LVEF and b) to determine the factors associated with worse HRQL. METHODS: Patients with symptomatic HF (NYHA Class II-IV) enrolled in the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) HRQL study completed the Minnesota Living with Heart Failure questionnaire at randomization. Patients were stratified into 2 HF cohorts: preserved LVEF (>40%) and low LVEF (

authors

  • Lewis, Eldrin F
  • Lamas, Gervasio A
  • O'Meara, Eileen
  • Granger, Christopher B
  • Dunlap, Mark E
  • McKelvie, Robert
  • Probstfield, Jeffrey L
  • Young, James B
  • Michelson, Eric L
  • Halling, Katarina
  • Carlsson, Jonas
  • Olofsson, Bertil
  • McMurray, John JV
  • Yusuf, Salim
  • Swedberg, Karl
  • Pfeffer, Marc A

publication date

  • January 2007

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