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In vivo cellularization of a cross-linked matrix...
Journal article

In vivo cellularization of a cross-linked matrix by intraperitoneal implantation: a new tool in heart valve tissue engineering

Abstract

AIM: To use in vivo instead of in vitro cell seeding in heart valve tissue engineering. METHODS AND RESULTS: Intraperitoneally preseeded, photo-oxidized bovine pericardial pulmonary valve constructs (group 1) were compared with non-preseeded constructs (group 2) implanted in sheep. All valves functioned normally and were macroscopically intact at explantation [1 week (n = 6) and 1 month (n = 6) in each group], except for one thrombosed leaflet …

Authors

De Visscher G; Vranken I; Lebacq A; Van Kerrebroeck C; Ganame J; Verbeken E; Flameng W

Journal

European Heart Journal, Vol. 28, No. 11, pp. 1389–1396

Publisher

Oxford University Press (OUP)

Publication Date

June 1, 2007

DOI

10.1093/eurheartj/ehl422

ISSN

0195-668X