Site of expression of immunity to Naegleria fowled in immunized mice Journal Articles uri icon

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abstract

  • Summary An experiment was performed which confirmed a previous finding that mice are protected against Naegleria fowleri infection by immunization with amoeba‐free supernatant from amoeba cultures. Histological observations suggested that this protection is expressed mainly at the nasal mucosa and possibly results from the combined effects of polymorphonuclear leucocyte‐mediated killing of the amoeba and mechanical elimination of the organisms by extensive shedding of necrotic epithelium.

publication date

  • January 1983