On The Preparation of Fluorine-18 Labelled XeF2 and Chemical Exchange between Fluoride Ion and XeF2

A recent report claims to have prepared [18F]XeF2 by exchange between a large stoichiometric excess of XeF2 and no-carrier-added 18F-, as salts of the [2,2,2-crypt-M+] (M = K or Cs) cations, in CH2Cl2 or CHCl3 solvents at room temperature. Attempts to repeat this work have proven unsuccessful and have led to a critical reinvestigation of chemical exchange between fluoride ion, in the form of anhydrous [N(CH3)4][F] and [2,2,2-crypt-K][F], and …