Sclerosing angiomatoid nodular transformation of the spleen: Case report Academic Article uri icon

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abstract

  • Sclerosing angiomatoid transformation of the spleen (SANT) is a relatively new, rare, and unique lesion that involves the spleen. Less than 30 cases have been described to date. The lesion commonly affects middle-aged adults and shows a female predilection. It is often discovered incidentally through imaging. SANT is morphologically and immunohistochemically distinct. However, as it is a relatively new entity, misdiagnosis of SANT may lead to overtreatment of the patients. The pathogenesis of SANT is unknown. The lesion is entirely benign, and splenectomy is curative. We report a new case of SANT, with emphasis on the differential diagnosis and pathogenesis of SANT.

publication date

  • April 2009