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An examination of neuropeptide Y postmortem...
Journal article

An examination of neuropeptide Y postmortem stability in an animal model simulating human autopsy conditions

Abstract

A rabbit antiserum to neuropeptide Y (NPY) was used to develop a radioimmunoassay for measuring NPY in brain tissue. By high-performance liquid chromatography, two peaks of immunoreactivity were detected in human postmortem cortex. A minor peak was seen at the void volume, while the majority of immunoreactivity comigrated with synthetic NPY standards. Using the Spokes-Koch rat model simulating human autopsy conditions, it was shown that …

Authors

Beal MF; Mazurek MF; Lorenz LJ; Chattiia GK; Ellison DW; Martin JB

Journal

Neuroscience Letters, Vol. 64, No. 1, pp. 69–74

Publisher

Elsevier

Publication Date

February 1986

DOI

10.1016/0304-3940(86)90665-8

ISSN

0304-3940