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Oxytocin in Alzheimer's disease: postmortem brain...
Journal article

Oxytocin in Alzheimer's disease: postmortem brain levels.

Abstract

Oxytocin (OXY) injected into the hippocampus is reported to interfere with the formation of memory in experimental animals. Memory impairment is one of the distinguishing features of Alzheimer's disease. We have studied OXY immunoreactivity in postmortem brain tissue from 12 cases of histologically confirmed Alzheimer's disease and 13 controls. OXY concentration was increased 33% in the hippocampus and temporal cortex of Alzheimer brains (p …

Authors

Mazurek MF; Beal MF; Bird ED; Martin JB

Journal

Neurology, Vol. 37, No. 6, pp. 1001–1003

Publisher

Wolters Kluwer

Publication Date

June 1987

DOI

10.1212/wnl.37.6.1001

ISSN

0028-3878