Journal article
Somatostatin and neuropeptide Y concentrations in pathologically graded cases of huntington's disease
Abstract
Somatostatin and neuropeptide Y concentrations have previously been reported to be increased in the basal ganglia in Huntington's disease (HD). In the present study we have extended these findings by examining both somatostatin-like immunoreactivity (SLI) and neuropeptide Y-like immunoreactivity (NPYLI) in cases of HD, which were graded according to the severity of pathological degeneration in the striatum. In addition, we surveyed a large …
Authors
Beal MF; Mazurek MF; Ellison DW; Swartz KJ; McGarvey U; Bird ED; Martin JB
Journal
Annals of Neurology, Vol. 23, No. 6, pp. 562–569
Publisher
Wiley
Publication Date
June 1988
DOI
10.1002/ana.410230606
ISSN
0364-5134