Journal article
Consequences of delayed therapy with second-line agents in rheumatoid arthritis: a 3 year followup on the hydroxychloroquine in early rheumatoid arthritis (HERA) study.
Abstract
OBJECTIVE: To assess the longterm effect of delaying therapy with second-line agents in patients with early rheumatoid arthritis (RA).
METHODS: One hundred nineteen patients who participated in a 9 month placebo controlled randomized trial of hydroxychloroquine sulfate (HCQ) were followed prospectively for an additional 3 years. Those randomized to HCQ are referred to as the early treatment group and those randomized to placebo as the delayed …
Authors
Tsakonas E; Fitzgerald AA; Fitzcharles MA; Cividino A; Thorne JC; M'Seffar A; Joseph L; Bombardier C; Esdaile JM
Journal
The Journal of Rheumatology, Vol. 27, No. 3, pp. 623–629
Publication Date
3 2000
ISSN
0315-162X