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Evidence for impaired skeletal load adaptation...
Journal article

Evidence for impaired skeletal load adaptation among Canadian women with type 2 diabetes mellitus: Insight into the BMD and bone fragility paradox

Abstract

OBJECTIVE: Recent data suggest that women with type 2 diabetes mellitus (T2DM) might be more susceptible to fractures due to an impaired adaptive response to mechanical load, despite reportedly higher bone mineral density (BMD). The purpose of this study was to use an engineering beam analysis to calculate and compare the load stresses on the femurs of healthy women and women with T2DM and compare these levels to conventional measures of …

Authors

Hamilton CJ; Jamal SA; Beck TJ; Khaled AS; Adachi JD; Brown JP; Davison KS; Group TCMOSR

Journal

Metabolism, Vol. 62, No. 10, pp. 1401–1405

Publisher

Elsevier

Publication Date

October 2013

DOI

10.1016/j.metabol.2013.05.004

ISSN

0026-0495