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Effect of Odanacatib on BMD and Fractures:...
Journal article

Effect of Odanacatib on BMD and Fractures: Estimates from Bayesian Univariate and Bivariate Meta-analyses

Abstract

CONTEXT: Odanacatib (ODN), a selective cathepsin-K inhibitor, was found to increase bone mineral density (BMD); the effect on fractures is based on adverse event reports. OBJECTIVE: To estimate current effects and predict future effects of ODN on BMD and fractures.

Authors

Gajic-Veljanoski O; Tomlinson G; Srighanthan J; Adachi JD; Josse R; Brown JP; Cheung AM

Journal

The Journal of Clinical Endocrinology & Metabolism, Vol. 99, No. 9, pp. 3070–3079

Publisher

The Endocrine Society

Publication Date

September 1, 2014

DOI

10.1210/jc.2014-1162

ISSN

0021-972X