Journal article
Effect of B-Vitamin Therapy on Progression of Diabetic Nephropathy: A Randomized Controlled Trial
Abstract
CONTEXT: Hyperhomocysteinemia is frequently observed in patients with diabetic nephropathy. B-vitamin therapy (folic acid, vitamin B(6), and vitamin B(12)) has been shown to lower the plasma concentration of homocysteine.
OBJECTIVE: To determine whether B-vitamin therapy can slow progression of diabetic nephropathy and prevent vascular complications.
Authors
House AA; Eliasziw M; Cattran DC; Churchill DN; Oliver MJ; Fine A; Dresser GK; Spence JD
Journal
JAMA: The Journal of the American Medical Association, Vol. 303, No. 16, pp. 1603–1609
Publisher
American Medical Association (AMA)
Publication Date
April 28, 2010
DOI
10.1001/jama.2010.490
ISSN
0098-7484