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D-dimer and factor VIIa in atrial fibrillation –...
Journal article

D-dimer and factor VIIa in atrial fibrillation – prognostic values for cardiovascular events and effects of anticoagulation therapy

Abstract

Coagulation markers may improve monitoring the risk of stroke and bleeding in patients with atrial fibrillation (AF) during anticoagulant treatment. We examined baseline levels of D-dimer and their association with stroke, cardiovascular death and major bleeding in 6,202 AF patients randomised to dabigatran or warfarin in the RE-LY trial. The effects of treatment on serial levels of D-dimer and coagulation factor (F) VIIa in 2,567 patients were …

Authors

Siegbahn A; Oldgren J; Andersson U; Ezekowitz MD; Reilly PA; Connolly SJ; Yusuf S; Wallentin L; Eikelboom JW

Journal

Thrombosis and Haemostasis, Vol. 115, No. 05, pp. 921–930

Publisher

Thieme

Publication Date

2016

DOI

10.1160/th15-07-0529

ISSN

0340-6245