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The novel biomarker-based ABC (age, biomarkers,...
Journal article

The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study

Abstract

BACKGROUND: The benefit of oral anticoagulation in atrial fibrillation is based on a balance between reduction in ischaemic stroke and increase in major bleeding. We aimed to develop and validate a new biomarker-based risk score to improve the prognostication of major bleeding in patients with atrial fibrillation. METHODS: We developed and internally validated a new biomarker-based risk score for major bleeding in 14,537 patients with atrial …

Authors

Hijazi Z; Oldgren J; Lindbäck J; Alexander JH; Connolly SJ; Eikelboom JW; Ezekowitz MD; Held C; Hylek EM; Lopes RD

Journal

The Lancet, Vol. 387, No. 10035, pp. 2302–2311

Publisher

Elsevier

Publication Date

June 2016

DOI

10.1016/s0140-6736(16)00741-8

ISSN

0140-6736