Journal article
How to Use an Article About Genetic Association: C: What Are the Results and Will They Help Me in Caring for My Patients?
Abstract
In the first 2 articles of this series, we reviewed the basic genetics concepts necessary to understand genetic association studies, and we enumerated the major issues in judging the validity of these studies. In this third article, we review the issues relating to the applicability of the results in the clinical situation. How large and precise are the associations? Many genetic effects are expected to be smaller in magnitude than traditional …
Authors
Attia J; Ioannidis JPA; Thakkinstian A; McEvoy M; Scott RJ; Minelli C; Thompson J; Infante-Rivard C; Guyatt G
Journal
JAMA: The Journal of the American Medical Association, Vol. 301, No. 3, pp. 304–308
Publisher
American Medical Association (AMA)
Publication Date
January 21, 2009
DOI
10.1001/jama.2008.993
ISSN
0098-7484