Journal article
Control of Pepsinogen Synthesis and Secretion
Abstract
The heterogeneous group of proteinases known as pepsinogens are synthesized, stored, and upon appropriate stimulation released from gastric mucosal chief cells. Under the acidic conditions of the lumen of the stomach, the proenzymes, pepsinogens, are converted to "pepsin", which plays an important physiologic role as a digestive enzyme. The potential roles for pepsin in upper gastrointestinal diseases such as gastric or duodenal ulcer and …
Authors
Muller MJ; Defize J; Hunt RH
Journal
Gastroenterology Clinics of North America, Vol. 19, No. 1, pp. 27–40
Publisher
Elsevier
Publication Date
March 1990
DOI
10.1016/s0889-8553(21)00455-6
ISSN
0889-8553