Journal article
Fluoxetine in the Treatment of Premenstrual Dysphoria
Abstract
BACKGROUND: Premenstrual dysphoria shares certain features with depression and anxiety states, which have been linked to serotonergic dysregulation. We evaluated the efficacy and safety of fluoxetine (which selectively inhibits the reuptake of serotonin) in the treatment of premenstrual dysphoria.
METHODS: The trial consisted of a single-blind, placebo washout period lasting two menstrual cycles, followed by a randomized, double-blind, …
Authors
Steiner M; Steinberg S; Stewart D; Carter D; Berger C; Reid R; Grover D; Streiner D
Journal
New England Journal of Medicine, Vol. 332, No. 23, pp. 1529–1534
Publisher
Massachusetts Medical Society
Publication Date
June 8, 1995
DOI
10.1056/nejm199506083322301
ISSN
0028-4793