Journal article
Inflammation-induced impairment of enteric nerve function in nematode-infected mice is macrophage dependent
Abstract
Trichinella spiralis infection in rodents is associated with suppression of ACh release from myenteric plexus that can be mimicked by macrophage-derived cytokines. We verified the presence of a macrophage infiltrate in the intestine during T. spiralis infection and determined the extent to which this cell type is responsible for the neural changes. C57BL/6 mice were infected with 375 T. spiralis larvae by gavage, and the presence of macrophages …
Authors
Galeazzi F; Haapala EM; van Rooijen N; Vallance BA; Collins SM
Journal
AJP Gastrointestinal and Liver Physiology, Vol. 278, No. 2, pp. g259–g265
Publisher
American Physiological Society
Publication Date
February 1, 2000
DOI
10.1152/ajpgi.2000.278.2.g259
ISSN
0193-1857