Journal article
Quantification of anti-angiogenesis using the capillaries of the chick chorioallantoic membrane demonstrates that the effect of human angiostatin is age-dependent
Abstract
We present a method whereby en face estimation of the chorionic capillary plexus can be generated in the living chick chorioallantoic membrane (CAM) and confirmed by post-fixation cross section analysis. This value does not alter significantly with age and provides a reliable and simple method to evaluate anti-angiogenesis. Anti-angiogenesis may be induced by an intervention, such as a pharmacological agent, applied to the surface of the CAM. …
Authors
Seidlitz E; Korbie D; Marien L; Richardson M; Singh G
Journal
Microvascular Research, Vol. 67, No. 2, pp. 105–116
Publisher
Elsevier
Publication Date
March 2004
DOI
10.1016/j.mvr.2003.12.005
ISSN
0026-2862