Journal article
Genome-wide Linkage Analyses of Quantitative and Categorical Autism Subphenotypes
Abstract
BACKGROUND: The search for susceptibility genes in autism and autism spectrum disorders (ASD) has been hindered by the possible small effects of individual genes and by genetic (locus) heterogeneity. To overcome these obstacles, one method is to use autism-related subphenotypes instead of the categorical diagnosis of autism since they may be more directly related to the underlying susceptibility loci. Another strategy is to analyze subsets of …
Authors
Liu X-Q; Paterson AD; Szatmari P; Consortium TAGP
Journal
Biological Psychiatry, Vol. 64, No. 7, pp. 561–570
Publisher
Elsevier
Publication Date
October 2008
DOI
10.1016/j.biopsych.2008.05.023
ISSN
0006-3223