Journal article
Impurities in commercial xanthine oxidase inhibit Ca pump and interfere in contractility of pig coronary artery
Abstract
Commercial, but not pure, preparations of xanthine oxidase in the absence of an aldehyde or xanthine were observed to inhibit Ca-uptake by the subcellular membranes isolated from the smooth muscle of the pig coronary artery. This inhibition was not due to xanthine oxidase but a contaminant in the preparation. The commercial preparation caused a greater relaxation of the PGF2 alpha contracted coronary artery than the pure enzyme. The tissues …
Authors
Grover AK; Samson SE
Journal
Biochemical and Biophysical Research Communications, Vol. 143, No. 2, pp. 575–581
Publisher
Elsevier
Publication Date
March 1987
DOI
10.1016/0006-291x(87)91392-1
ISSN
0006-291X