Journal article
Protection of Ca pump of coronary artery against inactivation by superoxide radical
Abstract
Superoxide radicals inactivate endoplasmic reticular (ER) Ca2+ pump in membranes isolated from smooth muscle of pig right coronary artery [Am. J. Physiol. 255 (Cell Physiol. 24): C297-C303, 1988]. We report on protective mechanisms against such inactivation. This tissue contained superoxide dismutase (SOD) and catalase. SOD was distributed primarily in cytosolic fraction, was cyanide sensitive, and was also present in mitochondrial fraction, …
Authors
Grover AK; Samson SE
Journal
American Journal of Physiology, Vol. 256, No. 3, pp. c666–c673
Publisher
American Physiological Society
Publication Date
March 1, 1989
DOI
10.1152/ajpcell.1989.256.3.c666
ISSN
0002-9513