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Keloid scarring, but not Dupuytren's contracture,...
Journal article

Keloid scarring, but not Dupuytren's contracture, is associated with unexplained carotid atherosclerosis.

Abstract

BACKGROUND: Atherosclerosis, a response to injury, may be thought of as scarring in the artery wall. TGF-beta and associated signaling molecules have been implicated in the pathophysiology of keloid scarring, Dupuytren's Contracture and atherosclerotic plaques in independent studies. PURPOSE: To test the hypothesis that excess cutaneous scarring and Dupuytren's contractures predispose independently to carotid atherosclerosis .

Authors

Bhavsar S; Nimigan A; Hackam DG; O'Gorman DB; Gan BS; Spence JD

Journal

Clinical & Investigative Medicine, Vol. 32, No. 2, pp. e95–102

Publisher

University of Toronto Press

Publication Date

April 1, 2009

DOI

10.25011/cim.v32i2.6026

ISSN

0147-958X