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Identification of fatty acid translocase on human...
Journal article

Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation

Abstract

Fatty acid translocase (FAT/CD36) is a transport protein with a high affinity for long-chain fatty acids (LCFA). It was recently identified on rat skeletal muscle mitochondrial membranes and found to be required for palmitate uptake and oxidation. Our aim was to identify the presence and elucidate the role of FAT/CD36 on human skeletal muscle mitochondrial membranes. We demonstrate that FAT/CD36 is present in highly purified human skeletal …

Authors

Bezaire V; Bruce CR; Heigenhauser GJF; Tandon NN; Glatz JFC; Luiken JJJF; Bonen A; Spriet LL

Journal

AJP Endocrinology and Metabolism, Vol. 290, No. 3, pp. e509–e515

Publisher

American Physiological Society

Publication Date

3 2006

DOI

10.1152/ajpendo.00312.2005

ISSN

0193-1849