Journal article
Hyperoxia decreases muscle glycogenolysis, lactate production, and lactate efflux during steady-state exercise
Abstract
The aim of this study was to determine whether the decreased muscle and blood lactate during exercise with hyperoxia (60% inspired O2) vs. room air is due to decreased muscle glycogenolysis, leading to decreased pyruvate and lactate production and efflux. We measured pyruvate oxidation via PDH, muscle pyruvate and lactate accumulation, and lactate and pyruvate efflux to estimate total pyruvate and lactate production during exercise. We …
Authors
Stellingwerff T; LeBlanc PJ; Hollidge MG; Heigenhauser GJF; Spriet LL
Journal
AJP Endocrinology and Metabolism, Vol. 290, No. 6, pp. e1180–e1190
Publisher
American Physiological Society
Publication Date
June 2006
DOI
10.1152/ajpendo.00499.2005
ISSN
0193-1849