Journal article
Role of endogenous prostaglandins in regulating the tone of opossum lower esophageal sphincter in vivo
Abstract
The role of prostaglandins in maintenance of basal myogenic tone of the lower esophageal sphincter (LES) of opossum has been studied in vivo. Intra-arterial infusion of arachidonic acid decreased LES tone, and this was inhibited by intravenous indomethacin (IDM) or intra-arterial 5,8,11,14-eicosatetraynoic acid (ETA). Alone these drugs did not reduce LES tone except transiently. In addition they did not affect relaxation of the LES to …
Authors
Daniel EE; Sarna S; Waterfall W; Crankshaw J
Journal
Prostaglandins, Vol. 17, No. 4, pp. 641–648
Publisher
Elsevier
Publication Date
April 1979
DOI
10.1016/0090-6980(79)90015-7
ISSN
0090-6980