Hemoglobin ontogeny during normal mouse fetal development. Journal Articles

abstract

• Pure populations of large, nucleated erythrocytes derived from yolk sac blood islands were obtained during normal fetal mouse development. Embryonic hemoglobins were present in these cells early in gestation. Later in gestation, an increasing amount of adults hemoglobin was also synthesized and accumulated in this population of primitive nucleated erythrocytes, as demonstrated by both biochemical and immunocytochemical techniques.

authors

• Brotherton, TW
• Chui, David Hing-kwei
• Gauldie, Jack
• Patterson, M

status

• published 

publication date

• June 1979

has subject area

• Animals (MeSH)
• Erythrocytes (MeSH)
• Female (MeSH)
• Fetus (MeSH)
• Hemoglobins (MeSH)
• Immunodiffusion (MeSH)
• Male (MeSH)
• Mice (MeSH)
• Mice, Inbred Strains (MeSH)
• Yolk Sac (MeSH)

published in

• Proceedings of the National Academy of Sciences of the United States of America  Journal

keywords

• Animals
• Erythrocytes
• Female
• Fetus
• Hemoglobins
• Immunodiffusion
• Male
• Mice
• Mice, Inbred Strains
• Yolk Sac

Digital Object Identifier (DOI)

• 10.1073/pnas.76.6.2853

start page

• 2853

end page

• 2857

volume

• 76

issue

• 6