Journal article
Cortical spreading depression in migraine-time to reconsider?
Abstract
New evidence concerning the pathophysiology of migraine has come from the results of therapeutic transcranial magnetic stimulation (tTMS). The instantaneous responses to single pulses applied during the aura or headache phase, together with a number of other observations, make it unlikely that cortical spreading depression is involved in migraine. tTMS is considered to act by abolishing abnormal impulse activity in cortical pyramidal neurons …
Authors
McComas AJ; Upton ARM
Journal
Arquivos de Neuro-Psiquiatria, Vol. 73, No. 8, pp. 714–721
Publisher
FapUNIFESP (SciELO)
Publication Date
August 2015
DOI
10.1590/0004-282x20150094
ISSN
0004-282X