Muscle metabolism and performance in perfused rat hindquarter during heavy exercise

An isolated perfused rat hindquarter model was used to examine muscle metabolism and performance during heavy muscular contraction. A one-pass system was used to perfuse the hindquarter for 30 min at rest and 20 min while electrically stimulated at 0.5 Hz with tetanic stimuli (100 Hz). The isometric tension generated by the gastrocnemius-plantaris-soleus muscle group was recorded continuously, and muscle biopsies were taken pre- and …