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Detrimental Effects of Hydralazine in Patients...
Journal article

Detrimental Effects of Hydralazine in Patients with Chronic Air-Flow Obstruction and Pulmonary Hypertension

Abstract

The acute effects of intravenously administered hydralazine on pulmonary hemodynamics and ejection radionuclide angiography were evaluated in 9 patients with chronic airflow obstruction (forced expiratory volume in one second, 1.2 +/- 0.8 L, mean +/- SD), pulmonary hypertension (mean pulmonary artery pressure (PAP), 29 +/- 13 mmHg), and sleep hypoxemia (maximal sleep desaturation, 20 +/- 16%). The effect of hydralazine was measured during both …

Authors

Tuxen DV; Powles ACP; Mathur PN; Pugsley SO; Campbell EJM

Journal

American Journal of Respiratory and Critical Care Medicine, Vol. 129, No. 3, pp. 388–395

Publication Date

March 1984

DOI

10.1164/arrd.1984.129.3.388

ISSN

1073-449X