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The dilution of benzalkonium chloride (BAK) in the...
Journal article

The dilution of benzalkonium chloride (BAK) in the tear Film

Abstract

The claim that benzalkonium chloride (BAK) synergistically enhances the antibiotic efficacy of gatifloxacin ophthalmic solution 0.3% (preserved with 0.005% BAK [50 μg/mL), Zymar; Allergan Inc., Irvine, Calif, USA) has been the subject of several studies. The purpose of this prospective clinical study was to test the hypothesis that BAK would be significantly diluted shortly after topical ocular administration and would thereafter have little or …

Authors

Friedlaender MH; Breshears D; Amoozgar B; Sheardown H; Senchyna M

Journal

Advances in Therapy, Vol. 23, No. 6, pp. 835–841

Publisher

Springer Nature

Publication Date

November 2006

DOI

10.1007/bf02850204

ISSN

0741-238X